{"id":425,"date":"2020-01-26T19:41:37","date_gmt":"2020-01-26T18:41:37","guid":{"rendered":"https:\/\/blogs.ugr.es\/photochem\/?p=425"},"modified":"2020-01-26T19:41:37","modified_gmt":"2020-01-26T18:41:37","slug":"microrna-detection-method","status":"publish","type":"post","link":"https:\/\/blogs.ugr.es\/photochem\/microrna-detection-method\/","title":{"rendered":"microRNA detection method"},"content":{"rendered":"<p>Our long-lasting collaboration with <strong>DestiNA Genomica<\/strong> and <strong>Optoi Microelectronics<\/strong>, within the framework of the <a href=\"https:\/\/optoi.com\/en\/applications\/research-and-development\/projects\/mirna-diseasy-home-page\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>miRNA-DisEASY<\/strong><\/a> project, has resulted in an exciting paper published in <em><a href=\"https:\/\/doi.org\/10.1039\/C9CC08069D\" target=\"_blank\" rel=\"noopener noreferrer\">Chemical Communications<\/a><\/em>.<\/p>\n<p>In this paper we describe a new method, using DestiNA&#8217;s dynamic labelling chemistry of nucleic acids and based on time-gated imaging, to detect abnormal levels in microRNA-122 in drug-induced liver damaged patients.<\/p>\n<p>This work opens up new lines in the continuous development of ultra-sensitive methods for biomarkers analyses in liquid biopsies.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1039\/C9CC08069D\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-426\" src=\"https:\/\/blogs.ugr.es\/photochem\/wp-content\/uploads\/sites\/61\/2020\/01\/toc-300x150.jpg\" alt=\"\" width=\"300\" height=\"150\" srcset=\"https:\/\/blogs.ugr.es\/photochem\/wp-content\/uploads\/sites\/61\/2020\/01\/toc-300x150.jpg 300w, https:\/\/blogs.ugr.es\/photochem\/wp-content\/uploads\/sites\/61\/2020\/01\/toc-700x350.jpg 700w, https:\/\/blogs.ugr.es\/photochem\/wp-content\/uploads\/sites\/61\/2020\/01\/toc.jpg 800w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a> <a href=\"https:\/\/optoi.com\/en\/applications\/research-and-development\/projects\/mirna-diseasy-home-page\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257\" src=\"https:\/\/blogs.ugr.es\/photochem\/wp-content\/uploads\/sites\/61\/2019\/04\/miRNA-DisEASY-logo.png\" alt=\"\" width=\"200\" height=\"101\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our long-lasting collaboration with DestiNA Genomica and Optoi Microelectronics, within the framework of the miRNA-DisEASY project, has resulted in an exciting paper published in Chemical Communications. In this paper we describe a new method, using DestiNA&#8217;s dynamic labelling chemistry of nucleic acids and based on time-gated imaging, to detect abnormal levels in microRNA-122 in drug-induced&hellip; <a href=\"https:\/\/blogs.ugr.es\/photochem\/microrna-detection-method\/\" class=\"more-link\">Leer m\u00e1s <span class=\"screen-reader-text\">acerca de microRNA detection method<\/span><\/a><\/p>\n","protected":false},"author":508,"featured_media":426,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[11],"tags":[12,15,8,9,10],"class_list":{"0":"post-425","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-papers","8":"tag-featured","9":"tag-mirna-diseasy","10":"tag-news","11":"tag-research","12":"tag-tg-diag","13":"entry"},"_links":{"self":[{"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/posts\/425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/users\/508"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/comments?post=425"}],"version-history":[{"count":1,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/posts\/425\/revisions"}],"predecessor-version":[{"id":427,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/posts\/425\/revisions\/427"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/media\/426"}],"wp:attachment":[{"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/media?parent=425"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/categories?post=425"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.ugr.es\/photochem\/wp-json\/wp\/v2\/tags?post=425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}