This research was carried out in the Antioxidants, Free Radicals and Nitric Oxide in Biotechnology and Agri-Food Research Group (Zaidín Experimental Station, CSIC, Granada). In recent years, this group has been investigating the possible contribution that peppers can make to a better state of health, thanks to the fact that they contain compounds of pharmacological and therapeutic interest. In collaboration with the University of Malaga and the MEDINA Foundation, we conducted metabolomic and transcriptomic studies to analyse a series of metabolic pathways that lead to the synthesis of molecules with this potential capacity. These molecules are also modulated by nitric oxide (NO), a molecule whose functions in the physiology of both animal and plant cells are increasingly recognised. This Master’s Thesis takes a step further in this strategy which, together with other metabolomic data recently obtained, has allowed the group to focus its research on quercetin, one of the flavonoid compounds present in peppers, which has a number of pharmacological properties.
Keywords: Pepper; nitric oxide (NO); quercetin; flavonoid compounds.
Directed by: José Manuel Palma Martínez